Biologique Recherche U-Fill PIGM 400 Anti-Dark Spot Micro-Cone Patches (Box of 12) are a technological innovation that enables the in-depth treatment of localized pigmentation irregularities. These individual patches covered with micro-cones target and release their brightening active ingredients as close as possible to melanocytes to visibly reduce the intensity of the pigmentation mark. Significantly reduces pigmentation marks, sun spots and dark age spots. Regulates the level of melanin in the various layers of the epidermis, limits melanogenesis, inhibits lipofuscin synthesis and deeply lightens hyper-pigmentation spots.

Regular use of the patches will help to decrease tyrosinase activity, the enzyme that leads to the production of melanin and decrease the level of melanin in the basal layer of the epidermis to lighten pigmentation marks and the area around the dark spot.

Active Ingredients: Anti-melanogenesis platform, Hexylresorcinol, Niacinamide, Tranexamic acid, Anti-glycation platform, L-Carnosine, Antioxidant platform, Vitamin C

Directions For Use: Apply after cleansing and Lotion P50 application preferably in the evening. Apply patches to clean dry skin, 3 times per week for 1 month. Remove the rigid transparent base and the white protective film. Press the side covered with micro-cones onto the specific mark to be treated. Gently tap the patch with your fingertips so that it sticks perfectly. Leave on overnight or at least for 3 hours. Remove and discard the patch. Follow with your preferred Quintessential and Targeted Serums, face cream, finishing serum and SPF sunscreen.