Gold-capped 1 oz glass bottle containing Biologique Recherche Serum Vivant, a brown/amber-colored liquid. On the bottle is a white label with a gold border, featuring text and the Biologique Recherche logo.
Serum Vivant
Gold-capped 0.3 oz glass bottle containing Biologique Recherche Serum Vivant, a brown/amber-colored liquid. On the bottle is a white label with a gold border, featuring text and the Biologique Recherche logo.
White background with orange/brown and dark blue text describing the main functions of Biologique Recherche Serum Vivant.
White background with orange/brown and dark blue text describing the results of clinical studies performed with Biologique Recherche Serum Vivant.
White background with orange/brown and dark blue text describing who the product is best for and what key ingredients are present.
Hand holding bottle of Biologique Recherche Serum Vivant, an amber-liquid. On the bottle is a white label with a gold border, featuring text and the Biologique Recherche logo. Freeflowing amber liquid pours down from the hand.
Woman's face on yellow/brown background with amber liquid pouring from above.
Close-up of a man's face with closed eyes and amber liquid dripping down the cheeks and over the eyebrows.
Woman looking into reflection on amber surface with white text over the image describing Biologique Recherche Serum Vivant product features.

Biologique Recherche

Serum Vivant

Persistent Blemish Corrector
$ 195.00

Daily quintessential serum to balance & treat congested skin, persistent blemishes, & control excess oil. Excellent skincare companion to the Masque Vivant.

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Size:1.0 fl oz - 30 ml
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Serum Vivant

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Pickup available at Paul Labrecque Salon & Skincare Spa New York Usually ready in 4 hours

Serum Vivant

1.0 fl oz - 30 ml

Paul Labrecque Salon & Skincare Spa New York

Pickup available, usually ready in 4 hours

5 East 57th Street
Floor 9
New York NY 10022
United States

+12129887816

Paul Labrecque Salon & Skincare Spa Palm Beach

Pickup available, usually ready in 4 hours

The Royal Poinciana Plaza, 50 Cocoanut Row
The Slat House, Suite 120
Palm Beach FL 33480
United States

+15614028207

Introducing the Biologique Recherche Serum Vivant. Building on the legacy of the cult-favorite Masque Vivant, Biologique Recherche Serum Vivant introduces the same purifying philosophy in a lightweight daily quintessential serum formulated to tone, balance, strengthen and purify congested skin struggling with persistent blemishes. 

Healthy-looking skin starts with a balanced microbiome. Rather than drying out blemishes or over-exfoliating the skin, Serum Vivant uses postbiotic, prebiotic and biomimetic ingredients to support its natural ecosystem. This helps promote a clearer complexion while keeping the skin barrier strong, balanced and comfortable.

Formulated for both morning and evening use, Serum Vivant fits seamlessly into any skincare regimen. Layering comfortably beneath moisturizers and SPF, it delivers daily support for clearer, smoother and healthier-looking skin while complementing the rest of your Biologique Recherche routine.

Yeast extract, the star of this show, helps support blemish-prone skin by supplying peptides, amino acids and antioxidants that help maintain the skin barrier and promote a healthier-looking complexion.

Inulin, a plant-derived prebiotic, encourages the growth of beneficial microorganisms in your skin barrier. Typically, anti-blemish treatments can be drying and/or irritating, and the addition of Inulin ensures comfort for those with sensitive skin. 

Polylysine is a naturally fermented ingredient that helps maintain a balanced skin surface by limiting the growth of unwanted microorganisms. This helps support clearer-looking skin and a more stable skin environment.


  • Calms the appearance of blemish-related redness for a more even-looking complexion
  • Formulated with prebiotics and postbiotics to balance your skin's microbiome, improving internal/external skin health
  • Reduces sebum and improves your skin's texture
  • Lightweight and silky formula effortlessly absorbs into the skin. Non-greasy finish
  • Supports skin barrier, promoting defense against environmental stressors
  • 42% persistent blemish reduction after 28 days
  • 27% excess sebum reduction after 14 days
  • 19% transepidermal water loss reduction after 28 days (helps the skin retain more moisture)

AM & PM use

After cleansing, apply a few drops to your face, neck and décolleté and massage in a light ascending motion until the serum has absorbed.

Apply after cleansing, toning with your Lotion P50 and applying your Masque Vivant. Follow with your Serum Vivant application. Cocktail with your other custom quintessential serums such as Serum Complexe Iribiol, Serum Dermopore, or Serum ISO Placenta.

Q: What is Biologique Recherche Serum Vivant?
A: Serum Vivant is a powerful daily anti-blemish treatment designed for skin prone to persistent breakouts and excess oil. Its formula helps reduce acne while supporting the skin microbiome and barrier. Biologique Recherche Serum Vivant is also safe for sensitive skin, with no excess dryness attributed to its use.

Q: What is the best way to use Serum Vivant?
A: Dispense a few drops of Biologique Recherche Serum Vivant into the palm of your hand, then use your fingertips to distribute the serum across the face, neck and décolleté. Massage it in with light, upward movements until fully absorbed, rather than rubbing aggressively or concentrating the entire dose on individual blemishes.

Q: What makes persistent blemishes different from occasional breakouts?
A: Persistent blemishes often come back alongside excess oil, redness, and a weakened skin barrier. Serum Vivant is designed for daily use to help keep these concerns under control by reducing the look of blemishes and excess sebum while supporting a more balanced skin environment. Because it also helps maintain moisture and comfort, its great for skin that becomes dry or irritated with harsher treatments.

Q: What skin type is Biologique Recherche Serum Vivant best for?
A: Serum Vivant is suitable for all skin types, though it is especially beneficial for acne-prone, oily, and combination skin. Its balancing formula helps address excess sebum, congestion, and recurring blemishes without making the skin feel stripped, so it can also work well for those dealing with breakouts alongside sensitivity or dry skin.

Q: How long does it take to see results with Serum Vivant?
A: Clinical testing showed a 27% reduction in excess sebum after 14 days and a 42% reduction in persistent blemishes after 28 days with regular use. Because blemish-prone skin can take time to rebalance, continued daily use may help support clearer, more even-looking skin over time. Individual results can vary depending on skin type, the severity of breakouts, and the rest of your routine.

Q: Can Biologique Recherche Serum Vivant be used with Masque Vivant?
A: Yes, rather than serving as a replacement, Serum Vivant compliments Masque Vivant by providing daily blemish treatment, while Masque Vivant serves as an intensive weekly treatment.
Used together, they can help address excess oil, congestion, and recurring blemishes on both a day-to-day and deeper treatment level.

Q: Does Serum Vivant reduce excess oil?
A: Biologique Recherche Serum Vivant is an excellent option for helping reduce excess oil. Designed with oily and combination skin in mind, it helps regulate sebum, minimize the look of blemishes, and keep congestion under control without leaving the skin feeling overly stripped.

Q: Can I use Biologique Recherche Serum Vivant as a spot treatment?
A: No, Serum Vivant is meant to be applied across the entire face, neck and décolleté. This allows the serum to help balance blemish-prone skin, support the skin barrier and address persistent imperfections more comprehensively than a spot treatment alone. The goal is to create an environment where imperfections cannot last.

Q: What makes Biologique Recherche Serum Vivant different from traditional blemish treatments?
A: Rather than relying on aggressive exfoliating or drying ingredients alone, Biologique Recherche Serum Vivant takes a microbiome-conscious approach to blemish care. Its postbiotic, prebiotic and biomimetic technologies help support the skin's natural ecosystem while promoting a clearer-looking complexion.

Q: Can I use Biologique Recherche Serum Vivant with other active skincare products?
A: Yes, but it is best to introduce combinations gradually, especially if you also use exfoliating acids, retinoids, or other blemish treatments. If your skin becomes dry, tight, or irritated, alternate active products or use them at different times of day to avoid overloading.

Q: What products pair well with Biologique Recherche Serum Vivant?
A: Serum Vivant integrates easily into an existing skincare routine and layers well beneath moisturizers. For those following a Biologique Recherche regimen, it also complements products like Lotion P50 and Masque Vivant for a more comprehensive approach to blemish-prone skin. If you're looking for an additional serum to layer with Biologique Recherche Serum Vivant, we recommend Serum Complex Iribiol for extra T-Zone support.

WATER (AQUA), GLYCERIN, METHYLPROPANEDIOL, YEAST EXTRACT, PROPANEDIOL, INULIN, GLYCERYL
CAPRYLATE/CAPRATE, LENS ESCULENTA (LENTIL) SEED EXTRACT, RHODOMYRTUS TOMENTOSA FRUIT EXTRACT, PUNICA GRANATUM PERICARP EXTRACT, PISTACIA LENTISCUS (MASTIC) GUM, BACILLUS FERMENT, ALTEROMONAS FERMENT EXTRACT, POLYLYSINE, PHYTIC ACID, MALTODEXTRIN, XANTHAN GUM, LECITHIN, GLYCERYL CAPRYLATE, PENTYLENE GLYCOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, PHENETHYL ALCOHOL, CAPRYLYL GLYCOL, POTASSIUM SORBATE, PHENYLPROPANOL, SODIUM HYDROXIDE, SODIUM BENZOATE, LEVULINIC ACID

Introducing Serum Vivant by Biologique Recherche