The right face cream is the quiet workhorse of every great skincare routine. It seals in hydration, protects the skin barrier and delivers treatment ingredients that keep working long after application. Biologique Recherche, the Paris-born, clinically minded skincare house, formulates its creams for specific skin types and conditions, never one-size-fits-all.
Below, the Paul Labrecque skincare team, the original Biologique Recherche spa partner in the USA since 1998, shares the Biologique Recherche face creams our clients return to again and again, matched to every skin type, along with the key ingredients to look for and how to use your cream morning and night.
Skincare Guide · Face Creams
SHOP The Full Biologique Recherche Skincare Collection- oily, Combination & Acne-Prone
- Sensitive, Reactive & Redness-Prone
- Dry & Lipid-Deficient
- Dehydrated, Dull & City-Stressed
- Dehydrated with Fine Lines
- Hyperpigmented & Uneven
- Mature, Fragile & Hormonally Changing
- The Ultimate Longevity Cream
Why a Good Face Cream Belongs in Your At-Home Routine
A face cream does far more than moisturize. Used consistently morning and evening, it is the step that protects and amplifies everything else in your routine.
Seals in Hydration
A well-formulated cream locks water into the skin and slows moisture loss, so skin stays supple, comfortable and plump from morning to night.
Strengthens the Barrier
Lipids, ceramide-like oils and soothing actives reinforce the skin’s protective barrier, the foundation of a calm, resilient complexion.
Delivers Targeted Actives
Your cream is not just a moisturizer. It carries treatment ingredients, from niacinamide to peptides, that keep working for hours after application.
Defends by Day
In the morning, antioxidants and protective ingredients help shield skin from pollution and daily environmental stress, beneath your SPF.
Repairs by Night
Overnight, skin shifts into renewal mode. A richer, reparative cream supports that natural regeneration while you sleep.
Compounds Over Time
Consistency is everything. Twice-daily use turns short-term comfort into long-term improvements in texture, tone and firmness.
“Biologique Recherche creams are formulated for the condition of your skin today, what the brand calls your Skin Instant©. Choose the cream for the skin you have, and it will reward you with every application.”The Paul Labrecque Skincare Team
Our Best-Selling Biologique Recherche Face Creams by Skin Type
Every cream below can be used morning and/or evening, applied after cleansing, applying your Lotion P50, masking and your quintessential and targeted serums.
Crème Dermopurifiante
$135.00
Our number-one best-selling cream for congested skin. This lightweight, purifying formula regulates excess oil and shine, helps clear and prevent breakouts, and refines the look of enlarged pores, all while soothing redness and supporting the skin barrier rather than stripping it.
Key ActivesNiacinamide, burdock, birch, centella asiatica, arnica, thyme, yeast extract
How to UseApply morning and/or evening after Lotion P50 and your serum. Massage into the face, neck and décolleté until fully absorbed.
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Crème V. Espoir
$135.00
An intense comfort cream for reactive complexions and skin prone to erythro-rosacea. It delivers immediate soothing comfort, visibly reduces redness and the appearance of small surface vessels, and restores a calmer, more even-looking tone.
Key ActivesNiacinamide, arnica, green tea, salvia miltiorrhiza, ophiopogon, lipid-rich emollients
How to UseApply morning and evening after cleansing and toning, massaging with deep, upward movements until completely absorbed.
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Crème Dermo RL
$225.00
A complete relipidating, protective and repairing cream that replenishes the skin's own lipid levels. Rich in precious seed oils and butters, it absorbs quickly and leaves dry skin plumper, softer and more comfortable, an essential through the colder months.
Key ActivesGrape, raspberry, cranberry and jojoba seed oils, shea butter, blackcurrant butter, hyaluronic acid
How to UseApply morning and/or evening after your toner and serum, massaging upward and outward over the face, neck and décolleté.
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Crème VIP O2
$225.00
The anti-pollution, oxygenating cream for “asphyxiated” skin that looks tired, grey and dull. The new formula helps defend against pollution and oxidative stress, restores radiance and refines texture, making it a favorite for busy New York and Palm Beach schedules.
Key ActivesMelatonin, hyaluronic acid, dandelion, tea tree, lavender, sunflower seed oil, yeast extract
How to UseApply morning and evening to the face, neck and décolleté with upward massage motions, after cleansing, toning and serums.
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Crème Elastine
$100.00
A line-correcting cream that helps prevent wrinkles from forming while smoothing the look of existing fine lines. It supports elasticity and tone, making it an ideal first anti-aging cream and an exceptional value.
Key ActivesElastin segment, rice protein, centella asiatica, vitamin B3, hyaluronic acid
How to UseApply morning and/or evening after Lotion P50 and your serum. Massage gently until absorbed.
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Crème PIGM 400
$330.00
A brightening, dark-spot correcting cream that helps reduce the intensity of existing pigmentation, prevents and limits the appearance of new spots, and unifies the complexion for a luminous, even finish.
Key ActivesFermented wasabi root, soy isoflavones, watercress sprout extract, sunflower seed oil, antioxidant chromanyl
How to UseApply morning and/or evening after toner and serum. Always follow with sun protection during the day.
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Crème MSR-H
$330.00
A firming, revitalizing cream created for mature, fine and fragile skin, and especially valued by women approaching or moving through menopause. It visibly plumps, firms and restores glow as skin changes.
Key ActivesWild yam and soy extracts, shea butter, shiitake extract, vitamin E, Biologique Recherche’s exclusive oxygen carrier
How to UseApply morning and/or evening after Lotion P50 and your serum, massaging into the face, neck and décolleté until absorbed.
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La Grande Crème
$750.00
Biologique Recherche’s most advanced cellular regenerating cream. It targets every sign of aging at once, restructuring and firming, smoothing wrinkles, and improving hydration and barrier function. It is the crowning step of a skin-longevity routine.
Key ActivesEpigenActiv®, acetyl hexapeptide-8, palmitoyl oligopeptide, royal jelly protein, green tea, shea butter
How to UseApply morning and/or evening after Lotion P50 and your serum with upward strokes. A deluxe sample size is available to try.
Shop La Grande Crème →The Key Ingredients to Look For, by Skin Type
The most effective face cream is the one whose ingredients match your skin’s needs. Here is what each skin type benefits from most, and where to find it.
| Skin Type | Key Ingredients | What They Do | Find Them In |
|---|---|---|---|
| Oily & Acne-Prone | Niacinamide · Burdock · Centella Asiatica | Regulate excess oil, purify congested pores and calm inflammation without over-drying. | Crème Dermopurifiante |
| Sensitive & Redness-Prone | Niacinamide · Arnica · Green Tea | Soothe reactivity, visibly reduce redness and reinforce a fragile barrier. | Crème V. Espoir |
| Dry | Seed Oils · Shea & Blackcurrant Butters · Hyaluronic Acid | Replenish the lipids dry skin lacks while drawing in and holding moisture. | Crème Dermo RL |
| Dehydrated & Dull | Melatonin · Hyaluronic Acid · Dandelion | Defend against pollution and oxidative stress while restoring hydration and radiance. | Crème VIP O2 |
| Fine Lines | Elastin Segment · Rice Protein · Vitamin B3 | Support elasticity and tone and smooth the look of fine lines. | Crème Elastine |
| Hyperpigmentation | Fermented Wasabi · Soy Isoflavones · Watercress Sprout | Help fade existing dark spots, limit new ones and even out the complexion. | Crème PIGM 400 |
| Mature & Hormonal | Wild Yam · Soy Extracts · Shea Butter | Firm, plump and nourish skin as it becomes finer and drier with hormonal change. | Crème MSR-H |
| Longevity (All Types) | Peptides · EpigenActiv® · Royal Jelly | Target multiple signs of aging at once for firmer, smoother, more resilient skin. | La Grande Crème |
How to Build Your Morning and Evening Cream Routine
Consistency is what transforms a beautiful cream into visible results. Follow the Biologique Recherche order of application twice a day.
☀ Morning: Protect
- Cleanse gently with a Biologique Recherche milk or cleanser suited to your skin.
- Apply Lotion P50 to exfoliate, rebalance and prepare the skin.
- Press in your serum.
- Massage in your face cream over the face, neck and décolleté.
- Finish with a broad-spectrum SPF.
☽ Evening: Repair
- Remove makeup, SPF and pollution with a thorough cleanse.
- Apply Lotion P50 to renew and refine.
- Layer your serum.
- Apply your face cream generously. Night is the ideal time for a reparative or anti-aging formula.
- Add a weekly mask as recommended by your skincare expert.
Quick-Reference Guide to Biologique Recherche Face Creams
| Skin Type | Face Cream | Hero Actives | Price |
|---|---|---|---|
| Oily, Combination & Acne-Prone | Crème Dermopurifiante | Niacinamide, burdock, birch | $135.00 |
| Sensitive, Reactive & Redness-Prone | Crème V. Espoir | Niacinamide, arnica, green tea | $135.00 |
| Dry & Lipid-Deficient | Crème Dermo RL | Grape, raspberry, cranberry and jojoba seed oils | $225.00 |
| Dehydrated, Dull & City-Stressed | Crème VIP O2 | Melatonin, hyaluronic acid, dandelion | $225.00 |
| Dehydrated with Fine Lines | Crème Elastine | Elastin segment, rice protein, centella asiatica | $100.00 |
| Hyperpigmented & Uneven | Crème PIGM 400 | Fermented wasabi root, soy isoflavones, watercress sprout extract | $330.00 |
| Mature, Fragile & Hormonally Changing | Crème MSR-H | Wild yam and soy extracts, shea butter, shiitake extract | $330.00 |
| The Ultimate Longevity Cream | La Grande Crème | EpigenActiv®, acetyl hexapeptide-8, palmitoyl oligopeptide | $750.00 |
Face Cream FAQs: Why AM & PM Consistency Matters
Why should I use a face cream both morning and night?
Your skin has different jobs at different times of day. In the morning, a face cream hydrates and helps protect skin from pollution, dryness and environmental stress. At night, skin shifts into repair mode, and your cream supports that natural renewal. Using a good face cream in both your AM and PM routine keeps hydration and barrier support constant, which is what delivers visible, lasting results.
Do I need a different face cream for morning and evening?
Not necessarily. Every Biologique Recherche cream featured here can be used morning and evening. Some clients choose to pair two creams, for example a protective, radiance-boosting cream like Crème VIP O2 in the morning and a more reparative or anti-aging cream like Crème Elastine or Crème MSR-H at night. A Paul Labrecque skincare expert can help you decide whether one cream or a pairing is right for your skin.
Do I still need a face cream if I use a serum?
Yes. Serums deliver concentrated actives deep into the skin, but most are not designed to seal in hydration or protect the barrier. Your face cream locks in your serum, prevents moisture loss and adds its own treatment ingredients. In the Biologique Recherche method, the order is Lotion P50, then serum, then cream.
Should oily or acne-prone skin skip moisturizer?
No. Skipping moisturizer can leave oily skin dehydrated, which often triggers even more oil production and irritation. The key is choosing the right formula. Crème Dermopurifiante is a lightweight, purifying cream that regulates shine and helps clear breakouts while keeping skin balanced and comfortable.
How long does it take to see results from a new face cream?
Many clients feel an immediate difference in comfort and hydration. Visible changes in texture, tone, fine lines or pigmentation typically build over four to eight weeks of consistent morning and evening use, as the skin moves through its natural renewal cycles. Consistency matters far more than quantity.
Should I apply face cream before or after sunscreen?
Apply your face cream first, allow it to absorb for a minute or two, then finish with a broad-spectrum SPF every morning. Daily sun protection is especially important when using brightening creams like Crème PIGM 400 or exfoliating toners like Lotion P50.
How much face cream should I use?
A pea- to almond-sized amount is usually enough for the face, with a little more for the neck and décolleté. Warm the cream between your fingertips and massage it in with upward, outward movements until fully absorbed. Using more will not speed up results, but using it consistently twice a day will.
How do I know which Biologique Recherche face cream is right for me?
Biologique Recherche formulates for your Skin Instant©, the condition of your skin today, rather than your age alone. Start with the skin-type guide above, then book a consultation with a Paul Labrecque skincare expert in New York or Palm Beach. As the original Biologique Recherche spa partner in the USA since 1998, we can assess your skin and build a personalized AM and PM routine.
Find Your Perfect Biologique Recherche Face Cream
Let a Paul Labrecque skincare expert, the original Biologique Recherche spa and retailer in the USA since 1998, assess your skin and build your personalized morning and evening routine, in salon or at home.
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